Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Slc20a1tm1.2Cmg Name: solute carrier family 20, member 1; targeted mutation 1.2, Cecilia M Giachelli MGI ID: MGI:4421036 Synonyms: PiT-1deltae3,4 Gene: Slc20a1  Location: Chr2:129040684-129053536 bp, + strand  Genetic Position: Chr2, 62.79 cM Alliance: Slc20a1tm1.2Cmg page

Slc20a1tm1.2Cmg/Slc20a1tm1.2Cmg embryos are developmentally delayed and anemic and yolk sacs lack mature vasculature Show the 1 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:156027
Parent Cell Line:	iTL BA1 (ES Cell)
Strain of Origin:	(C57BL/6NTac x 129S6/SvEvTac)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Cre mediated recombination removed exons 3 and 4. The absence of transcripts containing exon 2 was confirmed by semi-quantitative RT-PCR analysis on E11.5 embryo extracts. (J:156027)

Generation of the Slc20a1tm1.1Cmg and Slc20a1tm1.2Cmg alleles

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

8 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Slc20a1 Mutation:	36 strains or lines available

Original:	J:156027 Festing MH, et al., Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1. Genesis. 2009 Dec;47(12):858-63
All:	1 reference(s)