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Gt(ROSA)26Sortm1.2(CAG-EGFP)Fsh
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm1.2(CAG-EGFP)Fsh
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1.2, Gordon Fishell
MGI ID: MGI:4420764
Synonyms: R26 RCE-fsf-GFP, RCE:FRT
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm1.2(CAG-EGFP)Fsh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155164
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, Reporter)
Mutation:    Insertion
 
Mutation detailsCre mediated recombination removes the loxP flanked STOP cassette from Gt(ROSA)26Sortm1(CAG-EGFP)Fsh. After removal of the FRT-flanked STOP cassette by Flp-mediated recombination, EGFP reporter expression is directed to the cells/tissues dependent upon the expression pattern of the promoter driving FLP recombinase. (J:155164)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  942 strains or lines available
References
Original:  J:155164 Sousa VH, et al., Characterization of Nkx6-2-derived neocortical interneuron lineages. Cereb Cortex. 2009 Jul;19 Suppl 1:i1-10
All:  27 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory