Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Nexmiftm1(KOMP)Wtsi
Name:	neurite extension and migration factor; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID:	MGI:4419911
Synonyms:	C77370tm1(KOMP)Wtsi
Gene:	Nexmif  Location: ChrX:103121040-103244791 bp, - strand  Genetic Position: ChrX, 46.48 cM
Alliance:	Nexmiftm1(KOMP)Wtsi page
IMPC:	Nexmif gene page

Mutant Cell Lines:	EPD0411_7_B01, EPD0411_7_B02, EPD0411_7_H02
Germline Transmission:	Earliest citation of germline transmission: J:283395
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 4479 starting at position 103127410 and ending at position 103131889 of Chromosome X (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:148605, J:173534, J:283395)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Nexmif Mutation:	54 strains or lines available

Original:	J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:	4 reference(s)