Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Calcoco2tm1(KOMP)Wtsi
Name:	calcium binding and coiled-coil domain 2; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID:	MGI:4419466
Gene:	Calcoco2  Location: Chr11:95990152-96002790 bp, - strand  Genetic Position: Chr11, 59.4 cM, cytoband C
Alliance:	Calcoco2tm1(KOMP)Wtsi page
IMPC:	Calcoco2 gene page

Mutant Cell Lines:	EPD0392_6_A09, EPD0392_6_A10, EPD0392_6_B10, EPD0392_6_C10, EPD0392_6_D10, EPD0392_6_D11, EPD0392_6_E09, EPD0392_6_E10, EPD0392_6_E12, EPD0392_6_F10, EPD0392_6_F11
Germline Transmission:	Earliest citation of germline transmission: J:204812
Parent Cell Line:	JM8A3.N1 (ES Cell)
Strain of Origin:	C57BL/6N-Atm1Brd
Project Collection:	KOMP-CSD

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P   Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 5027 starting at position 95993439 and ending at position 95998466 of Chromosome 11 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. (J:148605, J:173534)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Calcoco2 Mutation:	39 strains or lines available

Original:	J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:	4 reference(s)