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Gene Expression Data
Assay Details
Assay
Reference: J:154140 Stephenson DT, et al., Immunohistochemical localization of phosphodiesterase 2A in multiple mammalian species. J Histochem Cytochem. 2009 Oct;57(10):933-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4418469
Gene symbol: Pde2a
Gene name: phosphodiesterase 2A, cGMP-stimulated
Antibody: PD2A-202AP
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 5A: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: brain Present Regionally restricted 5A Expression is in neurons and neuropil of the superficial layers of the developing neuroepithelium.
TS23: blood vessel Present Regionally restricted 5A Expression is in cerebrovascular endothelium.

Specimen 5C: embryonic day 15.0; Pde2atm1Dtst/Pde2atm1Dtst (more )
Structure Level Pattern Image Note
TS23: brain Absent 5C
TS23: blood vessel Absent 5C Absent in cerebrovascular endothelium.

Specimen 10C: postnatal (more )
Structure Level Pattern Image Note
TS28: adrenal gland zona glomerulosa Strong 10C

Specimen 10D: postnatal (more )
Structure Level Pattern Image Note
TS28: corpus striatum Present Regionally restricted 10D Expression is in the dorsolateral striatum adjacent to the corpus callosum.

Specimen Table 3: postnatal (more )
Structure Level Pattern Image Note
TS28: bronchiole epithelium Weak
TS28: epididymis Weak
TS28: seminiferous tubule Weak
TS28: small intestine epithelium Weak
TS28: blood vessel endothelium Moderate
TS28: cecum Moderate
TS28: colon epithelium Moderate
TS28: corpus luteum Moderate
TS28: detrusor muscle of bladder Moderate
TS28: dorsal root ganglion Moderate
TS28: myenteric nerve plexus Moderate
TS28: ovary follicle Moderate
TS28: pituitary gland Moderate
TS28: spleen red pulp Moderate
TS28: spleen white pulp Moderate
TS28: stomach epithelium Moderate
TS28: urothelium of bladder Moderate
TS28: thymus cortex Moderate Single cells Occasional round to polygonal cells in cortex and medulla.
TS28: thymus medullary core Moderate Single cells Occasional round to polygonal cells in cortex and medulla.
TS28: hemolymphoid system Moderate Regionally restricted Expression is weak to strong in gut-associated lymphatic tissue and in bronchial-associated lymphatic tissue.
TS28: adrenal gland Strong
TS28: ciliary epithelium Strong
TS28: enteric ganglion Strong
TS28: lymph node Strong
TS28: retina Strong
TS28: interstitium of the testis Absent
TS28: islets of Langerhans Absent
TS28: mammary gland Absent
TS28: metanephros Absent
TS28: prostate gland Absent
TS28: salivary gland Absent
TS28: skin Absent
TS28: thyroid gland Absent
TS28: tongue Absent
TS28: trachea Absent
TS28: uterus Absent

Specimen Not shown: postnatal (more )
Structure Level Pattern Image Note
TS28: amygdala Strong
TS28: corpus striatum Strong
TS28: dentate gyrus Strong
TS28: globus pallidus Strong
TS28: habenula Strong
TS28: hippocampus Strong
TS28: neocortex layer Strong
TS28: pallidum Strong
TS28: spinal cord dorsal horn Strong
TS28: substantia nigra Strong


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory