Summary | Mutation origin | Mutation description | Tumor data | Find Mice (IMSR) | References

Symbol:	Lfngtm1.1Egan
Name:	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; targeted mutation 1.1, Sean E Egan
MGI ID:	MGI:4418227
Synonyms:	Lfngflox
Gene:	Lfng  Location: Chr5:140593096-140601300 bp, + strand  Genetic Position: Chr5, 79.15 cM
Alliance:	Lfngtm1.1Egan page

Germline Transmission:	Earliest citation of germline transmission: J:155893
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 2 and a neo cassette flanked by loxP and FRT sites was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette leaving exon 2 floxed. (J:155893)

List all tumor models in MMHCdb carrying Lfngtm1.1Egan

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lfng Mutation:	32 strains or lines available

Original:	J:155893 Xu K, et al., Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. Am J Physiol Lung Cell Mol Physiol. 2010 Jan;298(1):L45-56
All:	8 reference(s)