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Gene Expression Data
Assay Details
Assay
Reference: J:154373 Town L, et al., The metalloendopeptidase gene Pitrm1 is regulated by hedgehog signaling in the developing mouse limb and is expressed in muscle progenitors. Dev Dyn. 2009 Oct 29;238(12):3175-3184
Assay type: RNA in situ
MGI Accession ID: MGI:4417964
Gene symbol: Pitrm1
Gene name: pitrilysin metallepetidase 1
Probe: Pitrm1 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch Present 3A Expression is present throughout the branchial arches.
TS17: fronto-nasal process Present Regionally restricted 3A Expression is present at the rostral tip of the frontonasal prominence.
TS17: brain Present 3A Expression is present throughout much of the neural epithelium and the ventricular/subventricular zones of many brain tissues.
TS17: brain ventricular layer Present 3A Expression is present throughout much of the neural epithelium and the ventricular/subventricular zones of many brain tissues.
TS17: neural tube Trace 3A Expression is barely detectable above background levels and is uniform across the dorsal-ventral axis.

Specimen 3B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: brain subventricular zone Present Regionally restricted 3B Expression is present in the ventricular/subventricular zones of many brain tissues.
TS21: brain ventricular layer Present Regionally restricted 3B Expression is present in the ventricular/subventricular zones of many brain tissues.
TS21: head mesenchyme Present Regionally restricted 3B Expression is present in the mesenchyme around the nasal conchae.
TS21: cerebral cortex ventricular layer Present 3B Expression is present in the ventricular zone of the neocortex.
TS21: midbrain Present Regionally restricted 3B Expression is present in the ventricular/subventricular zone of the tectum.

Specimen 3C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: brain subventricular zone Present Regionally restricted 3C Expression is present in the ventricular/subventricular zones of many brain tissues.
TS22: brain ventricular layer Present Regionally restricted 3C Expression is present in the ventricular/subventricular zones of many brain tissues.
TS22: head mesenchyme Present Regionally restricted 3C Expression is present in the mesenchyme around the nasal conchae.
TS22: incisor enamel organ Present Regionally restricted 3C , 3J Expression is present in the enamel organ.
TS22: molar enamel organ Present 3C
TS22: cerebral cortex ventricular layer Present 3C Expression is present in the ventricular zone of the neocortex.
TS22: tectum Present Regionally restricted 3C Expression is present in the ventricular/subventricular zone of the tectum.

Specimen 3D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: brain Present Regionally restricted 3D Expression is present in the ventricular/subventricular zones of many brain tissues.
TS23: brain subventricular zone Present Regionally restricted 3D Expression is present in the ventricular/subventricular zones of many brain tissues.
TS23: cerebellum Present Regionally restricted 3D Expression is present in the rhombic lip, in the ventricular zone, and the external granule cell layer of the cerebellum.
TS23: cerebellum external granule cell layer Present Regionally restricted 3D Expression is present in the rhombic lip, in the ventricular zone, and the external granule cell layer of the cerebellum.
TS23: cerebellum ventricular layer Present Regionally restricted 3D Expression is present in the rhombic lip, in the ventricular zone, and the external granule cell layer of the cerebellum.
TS23: incisor enamel organ Present 3D Expression is present in the enamel organ.
TS23: molar enamel organ Present 3D Expression is present in the enamel organ.
TS23: cerebral cortex ventricular layer Present 3D Expression is present in the ventricular zone of the neocortex.
TS23: hippocampus Present Regionally restricted 3D Expression is present in the ventricular/subventricular zone.
TS23: inferior colliculus Present Regionally restricted 3D Expression is present in the ventricular/subventricular zone.
TS23: superior colliculus Present Regionally restricted 3D Expression is present in the ventricular/subventricular zone.
TS23: lateral ganglionic eminence Present Regionally restricted 3D Expression is present in the ventricular/subventricular zone of the medial and lateral ganglionic eminences.
TS23: medial ganglionic eminence Present Regionally restricted 3D Expression is present in the ventricular/subventricular zone of the medial and lateral ganglionic eminences.

Specimen 3E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: brain subventricular zone Present Regionally restricted 3E Expression is present in the ventricular/subventricular zones of many brain tissues.
TS20: brain ventricular layer Present Regionally restricted 3E Expression is present in the ventricular/subventricular zones of many brain tissues.
TS20: cerebral cortex ventricular layer Present 3E Expression is present in the ventricular zone of the neocortex.
TS20: lateral ganglionic eminence Present Regionally restricted 3E Expression is present in the ventricular/subventricular zone of the medial and lateral ganglionic eminences.
TS20: medial ganglionic eminence Present Regionally restricted 3E Expression is present in the ventricular/subventricular zone of the medial and lateral ganglionic eminences.

Specimen 3F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: brain subventricular zone Present Regionally restricted 3F Expression is present in the ventricular/subventricular zones of many brain tissues.
TS21: brain ventricular layer Present Regionally restricted 3F Expression is present in the ventricular/subventricular zones of many brain tissues.
TS21: cerebral cortex ventricular layer Present 3F Expression is present in the ventricular zone of the neocortex.

Specimen 3G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: extrinsic ocular muscle Present 3G
TS22: masticatory muscle Present Regionally restricted 3G
TS22: tongue muscle Present 3G
TS22: head mesenchyme Present Regionally restricted 3G Expression is present in the mesenchyme around the nasal conchae.
TS22: lens Present 3G
TS22: retina Present 3G
TS22: incisor enamel organ Present 3G Expression is present in the enamel organ.
TS22: molar enamel organ Present 3G Expression is present in the enamel organ.
TS22: submandibular gland primordium epithelium Present 3G , 3I

Specimen 3H: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hair Present Regionally restricted 3P , 3O , 3H Expression is restricted to the hair matrix. It is present in the region on the upper side of the hair bulb and does not extend to the epithelial tissues further up the hair shaft.

Specimen 3K/L: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: molar enamel organ Present 3L , 3K

Specimen 3M: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: trunk musculature Present 3M Expression is present in the musculature of the body wall within the flank.

Specimen Not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: spinal cord Weak Expression is low in the neural tube.

Specimen 3N: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: trunk musculature Present 3N Expression is present in the musculature of the body wall.
TS21: spinal cord Weak 3N Expression is low in the neural tube.
TS21: lung epithelium Present 3N
TS21: lung mesenchyme Present 3N


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory