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Cacna1atm1Nobs
Targeted Allele Detail
Summary
Symbol: Cacna1atm1Nobs
Name: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; targeted mutation 1, Noboru Suzuki
MGI ID: MGI:4415271
Gene: Cacna1a  Location: Chr8:85065268-85366875 bp, + strand  Genetic Position: Chr8, 40.95 cM
Alliance: Cacna1atm1Nobs page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:155607
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA portion of exon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:155607, J:155724)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cacna1a Mutation:  115 strains or lines available
References
Original:  J:155724 Kulik A, et al., Immunocytochemical localization of the alpha 1A subunit of the P/Q-type calcium channel in the rat cerebellum. Eur J Neurosci. 2004 Apr;19(8):2169-78
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory