About   Help   FAQ
Id2tm2.1Blh
Targeted Allele Detail
Summary
Symbol: Id2tm2.1Blh
Name: inhibitor of DNA binding 2; targeted mutation 2.1, Brigid L Hogan
MGI ID: MGI:4398924
Synonyms: Id2-eGFP, Id2tm2(EGFP)Blh
Gene: Id2  Location: Chr12:25143798-25146091 bp, - strand  Genetic Position: Chr12, 8.57 cM, cytoband B
Alliance: Id2tm2.1Blh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:154450
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe targeting vector contained an EGFP cassette inserted at the translation initiation codon of the Id2 locus, replacing most of exon 1, except for the final 25 nucleotides. The cre cassette was followed by a frt-PGK-neo-frt cassette, which was removed by flp-mediated excision after germline transmission. (J:154450)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Id2 Mutation:  19 strains or lines available
References
Original:  J:154450 Rawlins EL, et al., The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells. Development. 2009 Nov;136(22):3741-5
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/09/2024
MGI 6.23
The Jackson Laboratory