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Gene Expression Data
Assay Details
Assay
Reference: J:81218 Gowen LC, et al., Targeted Disruption of the Osteoblast/Osteocyte Factor 45 Gene (OF45) Results in Increased Bone Formation and Bone Mass. J Biol Chem. 2003 Jan 17;278(3):1998-2007
Assay type: Immunohistochemistry
MGI Accession ID: MGI:4362121
Gene symbol: Mepe
Gene name: matrix extracellular phosphoglycoprotein with ASARM motif (bone)
Antibody: OF45 antibody
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen WT: postnatal (more )
Structure Level Pattern Image Note
TS28: tibia Present Regionally restricted 2_WT Expression is in osteocytes embedded in mineralized bone, absent in osteoblasts, lining cells, osteoclasts, chondrocytes, or periosteal cells.
Specimen KO: postnatal; Mepetm1Tbrw/Mepetm1Tbrw (more )
Structure Level Pattern Image Note
TS28: tibia Absent 2_KO
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory