Tg(Thy1-COL25A1)861Yfu
Transgene Detail
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| Symbol: |
Tg(Thy1-COL25A1)861Yfu |
| Name: |
transgene insertion 861, Ying-Hui Fu |
| MGI ID: |
MGI:4359741 |
| Transgene: |
Tg(Thy1-COL25A1)861Yfu Location: unknown
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| Alliance: |
Tg(Thy1-COL25A1)861Yfu page
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| Strain of Origin: |
(C57BL/6 x SJL)F2
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Thy1-COL25A1)861Yfu expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
COL25A1 (84570) |
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Mutation details: A human COL25A1 complementary cDNA (AF293340, nt507-2588 splice variant lacking nt952-969) was placed under the control of the Thy1 promoter. The protein product corresponds to AAK35008 without amino acids 141-146 in the COL1 domain. Two founders (861, and 797) showed abundant transgene expression.
(J:152747)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:152747 Tong Y, et al., COL25A1 triggers and promotes Alzheimer's disease-like pathology in vivo. Neurogenetics. 2010 Feb;11(1):41-52 |
| All: |
1 reference(s) |
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Analysis Tools
