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Bicc1tm1Bdc
Targeted Allele Detail
Summary
Symbol: Bicc1tm1Bdc
Name: BicC family RNA binding protein 1; targeted mutation 1, Daniel B Constam
MGI ID: MGI:4356450
Gene: Bicc1  Location: Chr10:70758662-70995530 bp, - strand  Genetic Position: Chr10, 36.75 cM
Alliance: Bicc1tm1Bdc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152173
Parent Cell Line:  GS1 (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsExons 5 through 11 were replaced with a neo cassette. This deletion splices exon 4 to exon 12 out of frame giving rise to a premature stop codon. (J:152173)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bicc1 Mutation:  65 strains or lines available
References
Original:  J:152173 Maisonneuve C, et al., Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow. Development. 2009 Sep;136(17):3019-30
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory