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Gene Expression Data
Assay Details
Assay
Reference: J:62085 Guillaume R, et al., Distinct and common developmental expression patterns of the murine pkd2 and pkd1 genes. Mech Dev. 2000 May;93(1-2):179-83
Assay type: RNA in situ
MGI Accession ID: MGI:4356187
Gene symbol: Pkd1
Gene name: polycystin 1, transient receptor potential channel interacting
Probe: Pkd1 cDNA4
Probe preparation: Antisense RNA
Results
Specimen 2--e6.5: embryonic day 6.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS9: embryo ectoderm Present 2_Pkd1 e6.5 Expression is seen over all the embryonic primordial layers.
TS9: embryo endoderm Present 2_Pkd1 e6.5 Expression is seen over all the embryonic primordial layers.
TS9: embryo mesoderm Present 2_Pkd1 e6.5 Expression is seen over all the embryonic primordial layers.
TS28: decidua Strong 2_Pkd1 e6.5 Strong expression is detected over the decidual region.

Specimen 2--e9.5 embryo: embryonic day 9.5 (more )
Note: This is a frontal section.
Structure Level Pattern Image Note
TS15: embryo Present 2_Pkd1 e9.5 Expression is pleitropic.
TS15: cardiac muscle tissue Trace 2_Pkd1 e9.5

Specimen 2--e9.5 mother: postnatal adult (more )
Note: This mother was carrying an E9.5 embryo.
Structure Level Pattern Image Note
TS28: myometrium Weak 2_Pkd1 e9.5

Specimen 2--e11.5: embryonic day 11.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS19: embryo mesenchyme Strong 2_Pkd1 e11.5
TS19: sclerotome Strong 2_Pkd1 e11.5
TS19: forebrain Strong 2_Pkd1 e11.5
TS19: hindbrain Strong 2_Pkd1 e11.5
TS19: midbrain Strong 2_Pkd1 e11.5

Specimen 2--e12.5: embryonic day 12.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS20: head mesenchyme Present Regionally restricted 2_Pkd1 e12.5 Expression is present in the mesenchyme of the face.
TS20: limb mesenchyme Present 2_Pkd1 e12.5
TS20: lung Present 2_Pkd1 e12.5
TS20: intestine Present 2_Pkd1 e12.5 Expression is present in the loops.
TS20: midgut Present 2_Pkd1 e12.5 Expression is present in the loops.
TS20: physiological umbilical hernia Present 2_Pkd1 e12.5 Expression is present in the umbilical cord.
TS20: metanephros Moderate Diffuse 2_Pkd1 e12.5
TS20: nose Strong Regionally restricted 2_Pkd1 e12.5 There is pronounced expression in nasal cartilaginous tissue.
TS20: vertebral cartilage condensation Strong 2_Pkd1 e12.5
TS20: cardiac muscle tissue Trace 2_Pkd1 e12.5
TS20: arch of aorta Strong 2_Pkd1 e12.5
TS20: atrioventricular endocardial cushion Strong 2_Pkd1 e12.5
TS20: ascending aorta Strong 2_Pkd1 e12.5 There is strong expression in the thoracic aorta.
TS20: dorsal aorta Strong 2_Pkd1 e12.5 There is strong expression in the thoracic aorta.
TS20: skeletal muscle Strong Regionally restricted 2_Pkd1 e12.5 There is strong expression in the diaphragm.
TS20: brain Present 2_Pkd1 e12.5
TS20: dorsal root ganglion Present 2_Pkd1 e12.5
TS20: spinal cord Present 2_Pkd1 e12.5

Specimen 2--e13.5: embryonic day 13.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS21: intestine mesenchyme Strong 2_Pkd1 e13.5 There is strong expression in the muscularis of the gastrointestinal loops.

Specimen 2--e15.5: embryonic day 15.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS23: metanephros Present 2_Pkd1 e15.5

Specimen Not shown: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: detrusor muscle of bladder Present

Specimen 2--e18.5: embryonic day 18.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS26: intestine mesenchyme Strong 2_Pkd1 e18.5 There is strong expression in the smooth muscle lamina propria and muscularis of the gastrointestinal loops.
TS26: lung Present 2_Pkd1 e18.5

Specimen 3A: embryonic day 15.5 (more )
Note: This is a parasagittal section.
Structure Level Pattern Image Note
TS23: renal cortex Present 3A
TS23: cortical renal tubule Present 3A , 3C
TS23: adrenal medulla Strong 3A There is strong expression in the adrenal medulla and capsule.

Specimen 3E: embryonic day 18.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS26: collecting duct Strong 3E
TS26: nephrogenic zone Strong 3E
TS26: cortical renal tubule Strong 3E
TS26: glomerular tuft Strong 3E

Specimen 3G: postnatal adult (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: renal cortex Present 3G
TS28: glomerular tuft Weak 3I , 3G
TS28: renal tubule Weak 3I , 3G
TS28: collecting duct Moderate 3G There is moderate expression in collecting tubules.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory