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Gene Expression Data
Assay Details
Assay
Reference: J:45496 Yamakawat K, et al., DSCAM: a novel member of the immunoglobulin superfamily maps in a Down syndrome region and is involved in the development of the nervous system. Hum Mol Genet. 1998 Feb;7(2):227-37
Assay type: RNA in situ
MGI Accession ID: MGI:4356078
Gene symbol: Dscam
Gene name: DS cell adhesion molecule
Probe: CHD2M-14
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen Not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Absent

Specimen 7A: embryonic day 9.5 (more )
Note: This is an oblique section.
Structure Level Pattern Image Note
TS15: central nervous system Present 7A Expression is present in the neuroepithelium.
TS15: branchial arch Weak Single cells 7A The expression is suggestive of being in migrating neural crest cells.
TS15: migrating neural crest Weak Single cells 7A The expression is suggestive of being in migrating neural crest cells.

Specimen 7B: embryonic day 9.5 (more )
Note: This is a transverse section.
Structure Level Pattern Image Note
TS15: branchial arch Weak 7B The expression is suggestive of being in migrating neural crest cells.
TS15: migrating neural crest Weak 7B The expression is suggestive of being in migrating neural crest cells.

Specimen Not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present
TS17: branchial arch Present

Specimen 7C: embryonic day 11.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS19: brain Present 7C Expression is abundant throughout the brain.
TS19: hindbrain Present 7C Expression is abundant throughout the brain.
TS19: telencephalon Present 7C Expression is abundant throughout the brain.
TS19: diencephalon Present 7C Expression is found in the thalamus.
TS19: myelencephalon Present 7C
TS19: olfactory epithelium Present 7C
TS19: dorsal root ganglion Present 7C
TS19: maxillary process Present Single cells 7C The expression is suggestive of being in migrating neural crest cells.
TS19: migrating neural crest Present Single cells 7C The expression is suggestive of being in migrating neural crest cells.
TS19: embryo mesenchyme Present Regionally restricted 7C Expression is present in the mesenchyme surrounding the umbilical vein and artery.
TS19: neural tube Present Non-Uniform 7C Expression is present in areas corresponding to where the motor neurons differentiate and within the lateral gray columns that later form commissural neurons.

Specimen 7E: embryonic day 11.5 (more )
Note: This is a frontal section.
Structure Level Pattern Image Note
TS19: brain Present 7E Expression is abundant throughout the brain.
TS19: dorsal root ganglion Present 7E
TS19: trigeminal ganglion Present 7E
TS19: gut Present Single cells 7E The expression is suggestive of being in migrating neural crest cells.
TS19: mandibular process Present Single cells 7E The expression is suggestive of being in migrating neural crest cells.
TS19: migrating neural crest Present Single cells 7E The expression is suggestive of being in migrating neural crest cells.
TS19: neural tube Present Non-Uniform 7E Expression is present in areas corresponding to where the motor neurons differentiate and within the lateral gray columns that later form commissural neurons.

Specimen 7F: embryonic day 12.5 (more )
Note: This is a transverse section.
Structure Level Pattern Image Note
TS20: spinal cord Present Non-Uniform 7F Expression is present in areas corresponding to where the motor neurons differentiate and within the lateral gray columns that later form commissural neurons.
TS20: dorsal root ganglion Present 7F

Specimen 7G: embryonic day 12.5 (more )
Note: This is a parasagittal section.
Structure Level Pattern Image Note
TS20: brain Present 7G
TS20: midbrain Present 7G Expression is present in a large portion of the midbrain.
TS20: pons Present 7G Expression is present in the pontine areas.
TS20: telencephalon Present Regionally restricted 7G Expression is present in the basal ganglia.
TS20: cerebral cortex mantle layer Present 7G Expression is present in the outermost layer of the cortex.

Specimen 7H: embryonic day 13.5 (more )
Note: This is a parasagittal section.
Structure Level Pattern Image Note
TS21: brain Present 7H Expression is present throughout most of the brain.

Specimen 7I: embryonic day 13.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS21: enteric nervous system Present 7I Expression is present in the outermost layer of the gut in cells that will form the myenteric ganglia.

Specimen 7J: embryonic day 15.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS23: peripheral nervous system Present Regionally restricted 7J Expression is present in the heart ganglion.

Specimen 7K: embryonic day 15.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS23: seminiferous cord Present 7K Expression is present in the epithelium of the seminiferous tubules.

Specimen 7L: embryonic day 16.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS24: vibrissa follicle Present 7L Expression is present in the regions of the snout that will develop into the sensory structures at the base of the vibrissae.

Specimen Not shown: embryonic day 15.5-16.5 (more )
Structure Level Pattern Image Note
TS24: peripheral nervous system Present Expression is present in most, if not all, of the neural crest-derived structures, including the pancreatic ganglia.
TS24: enteric nervous system Present
TS24: peripheral nerve trunk Present
TS24: annulus fibrosus Present
TS24: main olfactory bulb Present Regionally restricted Expression is present in the granule cells and within the tufted mitral cells.

Specimen Not shown: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: hippocampus Present Expression is most extensive within differentiating regions of the brain.
TS27: inferior colliculus Present Expression is most extensive within differentiating regions of the brain.
TS27: main olfactory bulb Present Expression is most extensive within differentiating regions of the brain.
TS27: telencephalon septum Present Expression is most extensive within differentiating regions of the brain.

Specimen 7M: postnatal adult (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 7M
TS28: deep cerebellar nucleus Present 7M

Specimen Not shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: amygdala Present
TS28: cerebral cortex Present
TS28: hippocampus Present
TS28: thalamus Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory