Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Asic3tm1Pho
Name:	acid-sensing ion channel 3; targeted mutation 1, Peter Holzer
MGI ID:	MGI:4353615
Synonyms:	ASIC#-
Gene:	Asic3  Location: Chr5:24618449-24622836 bp, + strand  Genetic Position: Chr5, 11.72 cM
Alliance:	Asic3tm1Pho page

Germline Transmission:	Earliest citation of germline transmission: J:151304
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A floxed neomycin cassette replaced part of exon 1, and all of exons 2-7. Southern blotting confirmed correct targeting took place. (J:151304)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Asic3 Mutation:	29 strains or lines available

Original:	J:151304 Wultsch T, et al., Deletion of the acid-sensing ion channel ASIC3 prevents gastritis-induced acid hyperresponsiveness of the stomach-brainstem axis. Pain. 2008 Feb;134(3):245-53
All:	4 reference(s)