Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dyrk1aGt(XQ0369)Wtsi
Name:	dual-specificity tyrosine phosphorylation regulated kinase 1a; gene trap XQ0369, Wellcome Trust Sanger Institute
MGI ID:	MGI:4338238
Synonyms:	Dyrk1am1
Gene:	Dyrk1a  Location: Chr16:94370869-94496376 bp, + strand  Genetic Position: Chr16, 55.3 cM
Alliance:	Dyrk1aGt(XQ0369)Wtsi page

Mutant Cell Line:	XQ0369
Germline Transmission:	Earliest citation of germline transmission: J:224899
Parent Cell Line:	E14TG2a.4 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Sanger Inst. Gene Trap Res.

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector     Vector: pGT0lxf   Mutation details: The beta-geo containing gene trap vector inserted in intron 4 resulting in disruption of the 321 amino acid kinase domain. (J:224899) Sequence Tags:  Sequence tag details (1 tag) Tag ID GenBank ID Method Tag Location (trapped strand)* Select XQ0369 CL256654 (MGI Seq Detail) 5' RACE Chr16:94466858-94466962 bp (+) * GRCm39 (strand of gene trap mutagenesis) Selected Tags: download BLAST at NCBI Genome Context:  Genome Browser view of this mutation 105 gene trap insertions have trapped this gene View all gene trap sequence tags in this region

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dyrk1a Mutation:	112 strains or lines available

Original:	J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:	2 reference(s)