Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Brk1Gt(DC0002)Wtsi
Name:	BRICK1, SCAR/WAVE actin-nucleating complex subunit; gene trap DC0002, Wellcome Trust Sanger Institute
MGI ID:	MGI:3872157
Gene:	Brk1  Location: Chr6:113581733-113593912 bp, + strand  Genetic Position: Chr6, 52.81 cM
Alliance:	Brk1Gt(DC0002)Wtsi page

Mutant Cell Line:	DC0002
Germline Transmission:	Earliest citation of germline transmission: J:166082
Parent Cell Line:	E14TG2a.4 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Sanger Inst. Gene Trap Res.

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector     Vector: pGT1lxr   Mutation details: The gene trap vector inserted into intron 1 between positions 10,139,050 and 10,139,051. The mutant transcript includes the first 42 amino acids of the gene fused to the beta-geo and noemyocin resistance genes. (J:166082) Sequence Tags:  Sequence tag details (1 tag) Tag ID GenBank ID Method Tag Location (trapped strand)* Select DC0002 DU709680 (MGI Seq Detail) 5' RACE Chr6:113581718-113581856 bp (+) * GRCm39 (strand of gene trap mutagenesis) Selected Tags: download BLAST at NCBI Genome Context:  Genome Browser view of this mutation 20 gene trap insertions have trapped this gene View all gene trap sequence tags in this region

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	31 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Brk1 Mutation:	15 strains or lines available

Original:	J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:	2 reference(s)