Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(GFAP-CRYAB)141.6Mes
Name:	transgene insertion 141.6, Albee Messing
MGI ID:	MGI:3850461
Synonyms:	CryabTg, CryabTg
Transgene:	Tg(GFAP-CRYAB)141.6Mes  Location: unknown
Alliance:	Tg(GFAP-CRYAB)141.6Mes page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(GFAP-CRYAB)141.6Mes expresses 1 gene Transgene expresses: Organism Expressed Gene Note hamster Cryab (101827485)   Mutation details: A transgenic construct containing the hamster Cryab, alpha B crystalline gene under the control of the human GFAP, glial fibrillary acidic protein, promoter was injected into fertilized FVB/N mouse eggs. Founder line 141.6 was subsequently established. (J:146191)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:146191 Hagemann TL, et al., Suppression of GFAP toxicity by alphaB-crystallin in mouse models of Alexander disease. Hum Mol Genet. 2009 Apr 1;18(7):1190-9
All:	2 reference(s)