Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ampd2m4521Dajl
Name:	adenosine monophosphate deaminase 2; mutation 4521 David J Lloyd
MGI ID:	MGI:3848348
Synonyms:	Ampd2m, B6m
Gene:	Ampd2  Location: Chr3:107981378-107993967 bp, - strand  Genetic Position: Chr3, 46.83 cM
Alliance:	Ampd2m4521Dajl page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: ENU mutagenesis induced a G to T transversion that results in the amino acid substitution of alanine to serine at position 341 (A341S). Western blot analysis confirmed the absence of protein expression in the liver of homozygotes and partial loss in the liver of heterozygotes. (J:223083) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ampd2 Mutation:	44 strains or lines available

Original:	J:149088 Juan T, et al., Identification of three loci affecting HDL-cholesterol levels in a screen for chemically induced recessive mutations in mice. J Lipid Res. 2009 Mar;50(3):534-45
All:	2 reference(s)