Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Tg(FCER1A)1Bhk
Name:	transgene insertion 1, Beverly H Koller
MGI ID:	MGI:3846551
Synonyms:	hFcepsilonR1alpha- hFcepsilonR1alpha+, hFcepsilonR1alphaTg
Transgene:	Tg(FCER1A)1Bhk  Location: unknown
Alliance:	Tg(FCER1A)1Bhk page

Germline Transmission:	Earliest citation of germline transmission: J:113572
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129P2/OlaHsd

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(FCER1A)1Bhk expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human FCER1A (2205) Fcer1a  (MGI:95494)   Mutation details: The transgenic construct contains the entire human Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, (FCER1A), including 2.9kb of upstream sequence. The transgene was coinjected with a plasmid containing the hprt minigene. These constructs were transfected into ES65-154 (E14TG2a-165) embryonic stem (ES). (J:113572)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:113572 Dombrowicz D, et al., Anaphylaxis mediated through a humanized high affinity IgE receptor. J Immunol. 1996 Aug 15;157(4):1645-51
All:	9 reference(s)