Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Trim32Gt(BGA355)Byg
Name:	tripartite motif-containing 32; gene trap BGA355, BayGenomics
MGI ID:	MGI:3837468
Gene:	Trim32  Location: Chr4:65523223-65534475 bp, + strand  Genetic Position: Chr4, 34.43 cM, cytoband C1
Alliance:	Trim32Gt(BGA355)Byg page

Mutant Cell Line:	BGA355
Germline Transmission:	Earliest citation of germline transmission: J:146155
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector     Vector: pGT1Lxf     Vector Type: gene trap   Mutation details: The gene trap vector, containing a beta-geo cassette, inserted at nucleotide 410 within exon 2. The absence of transcript expression was confirmed by RT-PCR analysis on brain extracts. Note transcript expression of the flanking gene is normal as confirmed by RT-PCR analysis on brain and skeletal muscle extracts. (J:146155) Sequence Tags:  Sequence tag details (1 tag) Tag ID GenBank ID Method Tag Location (trapped strand)* Select BGA355 CW509319 (MGI Seq Detail) 5' RACE Chr4:65531559-65531660 bp (+) * GRCm39 (strand of gene trap mutagenesis) Selected Tags: download BLAST at NCBI Genome Context:  Genome Browser view of this mutation 2 gene trap insertions have trapped this gene View all gene trap sequence tags in this region

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trim32 Mutation:	27 strains or lines available

Original:	J:146155 Kudryashova E, et al., Deficiency of the E3 ubiquitin ligase TRIM32 in mice leads to a myopathy with a neurogenic component. Hum Mol Genet. 2009 Apr 1;18(7):1353-67
All:	10 reference(s)