Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Aox4tm1Enga
Name:	aldehyde oxidase 4; targeted mutation 1, Enrico Garattini
MGI ID:	MGI:3833684
Synonyms:	Aoh2-
Gene:	Aox4  Location: Chr1:58249556-58307756 bp, + strand  Genetic Position: Chr1, 28.97 cM
Alliance:	Aox4tm1Enga page

Germline Transmission:	Earliest citation of germline transmission: J:145029
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 22 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on extracts from the skin, Haderian glands, and liver. (J:145029)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aox4 Mutation:	79 strains or lines available

Original:	J:145029 Terao M, et al., Role of the molybdoflavoenzyme aldehyde oxidase homolog 2 in the biosynthesis of retinoic acid: generation and characterization of a knockout mouse. Mol Cell Biol. 2009 Jan;29(2):357-77
All:	2 reference(s)