Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Kalrntm1Npl
Name:	kalirin, RhoGEF kinase; targeted mutation 1, Neuropeptide Laboratory
MGI ID:	MGI:3831288
Synonyms:	Kal7CKO, Kalrntm1Riem
Gene:	Kalrn  Location: Chr16:33789443-34393647 bp, - strand  Genetic Position: Chr16, 24.27 cM
Alliance:	Kalrntm1Npl page

Germline Transmission:	Earliest citation of germline transmission: J:142364
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of the exon specific for the Kalrn-7 isoform, and an frt-flanked neo cassette with a 3' loxP site was inserted downstream of the exon. Germ line, flp-mediated recombination was used to remove the neo cassette leaving the isoform specific exon floxed. (J:142364)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kalrn Mutation:	170 strains or lines available

Original:	J:142364 Ma XM, et al., Kalirin-7 is required for synaptic structure and function. J Neurosci. 2008 Nov 19;28(47):12368-82
All:	2 reference(s)