Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Myh6/tetO-POSTN)22.1Jmol
Name:	transgene insertion 22.1, Jeffery D Molkentin
MGI ID:	MGI:3819377
Synonyms:	alpha-MHC-Pn
Transgene:	Tg(Myh6/tetO-POSTN)22.1Jmol  Location: unknown
Alliance:	Tg(Myh6/tetO-POSTN)22.1Jmol page

Strain of Origin:

FVB/N

Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence) Inducer:    doxycycline/tetracycline Mutation:    Insertion   Tg(Myh6/tetO-POSTN)22.1Jmol expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human POSTN (10631) Postn  (MGI:1926321)   Mutation details: The alpha myosin heavy chain fused to a tet-responsive promoter element (tetO) was used to drive repressible cardiac muscle-specific expression of the human gene. (J:140301)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:140301 Oka T, et al., Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling. Circ Res. 2007 Aug 3;101(3):313-21
All:	2 reference(s)