Summary | Mutation origin | Mutation description | Expression | Find Mice (IMSR) | References

Symbol:	Rorctm3Litt
Name:	RAR-related orphan receptor gamma; targeted mutation 3, Dan R Littman
MGI ID:	MGI:3818459
Synonyms:	RORgammaflox
Gene:	Rorc  Location: Chr3:94280101-94305583 bp, + strand  Genetic Position: Chr3, 40.56 cM, cytoband F2
Alliance:	Rorctm3Litt page

Germline Transmission:	Earliest citation of germline transmission: J:229446
Parent Cell Line:	CY2.4 (ES Cell)
Strain of Origin:	B6(Cg)-Tyrc-2J

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exons 3-6 of the targeted gene are flanked by loxP sites. A floxed neomycin resistance gene used in the construction of this strain was deleted by partial recombination. (J:229446)

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rorc Mutation:	42 strains or lines available

Original:	J:229446 Choi GB, et al., The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring. Science. 2016 Feb 26;351(6276):933-9
All:	33 reference(s)