Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Igk*A)A02Dgs
Name:	transgene insertion A02, David G Schatz
MGI ID:	MGI:3811481
Synonyms:	TgA
Transgene:	Tg(Igk*A)A02Dgs  Location: unknown
Alliance:	Tg(Igk*A)A02Dgs page

Strain of Origin:

C57BL/6 and SJL

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Igk*A)A02Dgs expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Igk (MGI:96494)   Mutation details: Vk167/PEPS is a transgene with a truncated region upstream of the promoter. The Igk (immunoglobulin kappa) sequence was further modified in the current strain through the insertion of 5 tandem repeats of a 20-bp adenine/thymine (A/T) fragment near the 3' end of the variable region. This "TgA" line has an A/T sequence comparable to that found in line "TgG" without the single cytosine:guanine (C:G) insert. (J:139793)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:139793 Unniraman S, et al., Strand-biased spreading of mutations during somatic hypermutation. Science. 2007 Aug 31;317(5842):1227-30
All:	1 reference(s)