Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(THY1-SNCA*A30P)M30Sud
Name:	transgene insertion M30, Thomas C Sudhof
MGI ID:	MGI:3810438
Synonyms:	M30
Transgene:	Tg(THY1-SNCA*A30P)M30Sud  Location: unknown
Alliance:	Tg(THY1-SNCA*A30P)M30Sud page

Strain of Origin:

(C57BL/6J x SJL/J)F1

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(THY1-SNCA*A30P)M30Sud expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human SNCA (6622) Snca  (MGI:1277151)   Mutation details: The transgene construct contains the human A30P mutant SNCA (synuclein, alpha) gene under the control of a human THY1 (thymus cell antigen 1, theta) promoter. Expression of the transgene is 5-fold higher in the brain and 10-fold higher in the spinal cord. (J:115193)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:115193 Chandra S, et al., Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. Cell. 2005 Nov 4;123(3):383-96
All:	4 reference(s)