Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Akap5tm1Jsco
Name:	A kinase anchor protein 5; targeted mutation 1, John D Scott
MGI ID:	MGI:3809936
Synonyms:	Akap5tm1Jscoe
Gene:	Akap5  Location: Chr12:76371665-76380927 bp, + strand  Genetic Position: Chr12, 33.73 cM
Alliance:	Akap5tm1Jsco page

Germline Transmission:	Earliest citation of germline transmission: J:138972
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: The loxP sites were introduced into both 5' and 3' of a single coding exon of the gene. A FRT flanked neo cassette was also introduced at down stream of the exon by homologous recombination in ES cells, and after germline transmission, removed by crossing with Flp expressing mice leaving loxP flanked coding exon. (J:138972)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Akap5 Mutation:	27 strains or lines available

Original:	J:138972 Tunquist BJ, et al., Loss of AKAP150 perturbs distinct neuronal processes in mice. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12557-62
All:	5 reference(s)