Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Prnp-APP695*/EYFP)49Gsn
Name:	transgene insertion 49, Lawrence SB Goldstein
MGI ID:	MGI:3809833
Synonyms:	APP-YFP
Transgene:	Tg(Prnp-APP695*/EYFP)49Gsn  Location: unknown
Alliance:	Tg(Prnp-APP695*/EYFP)49Gsn page

Strain of Origin:

(BALB/c x C57BL/6)F1

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence, Reporter) Mutation:    Insertion   Mutation details: The mouse prion protein promoter drives expression of the carboxy terminal portion of human amyloid precursor protein 695 (APP695) fused to enhanced yellow fluorescent protein (EYFP). Expression in brain, spinal cord and sciatic nerve has been confirmed by Western blot. Primary hippocampal cultures express EYFP at low levels. (J:139717)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:139717 Goldstein LS, Generation of a human APP695-EYFP fusion transgenic allele. MGI Direct Data Submission. 2008;
All:	1 reference(s)