Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kif5btm1Njen
Name:	kinesin family member 5B; targeted mutation 1, Nancy A Jenkins
MGI ID:	MGI:3809821
Synonyms:	Kif5Bfl, Kinesin-1B II
Gene:	Kif5b  Location: Chr18:6201005-6241524 bp, - strand  Genetic Position: Chr18, 4.46 cM, cytoband A2-B1
Alliance:	Kif5btm1Njen page

Germline Transmission:	Earliest citation of germline transmission: J:170198
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 2 is flanked by loxP sites. An FRT-flanked neo cassette was removed by flp-mediated recombination. (J:170198)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kif5b Mutation:	59 strains or lines available

Original:	J:170198 Cui J, et al., Targeted inactivation of kinesin-1 in pancreatic beta-cells in vivo leads to insulin secretory deficiency. Diabetes. 2011 Jan;60(1):320-30
All:	13 reference(s)