Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Trib2tm1Ryn
Name:	tribbles pseudokinase 2; targeted mutation 1, Ryuichi Nishinakamura
MGI ID:	MGI:3806571
Synonyms:	Trb2-lacZ
Gene:	Trib2  Location: Chr12:15841728-15866923 bp, - strand  Genetic Position: Chr12, 7.25 cM
Alliance:	Trib2tm1Ryn page

Germline Transmission:	Earliest citation of germline transmission: J:138553
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: The coding region of exon 1 from 44 bp upstream of the translation initiation codon was replaced with a lacZ and floxed neo cassette sandwiched between lox71 and loxP sites. (J:138553)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

21 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trib2 Mutation:	28 strains or lines available

Original:	J:138553 Takasato M, et al., Trb2, a mouse homolog of tribbles, is dispensable for kidney and mouse development. Biochem Biophys Res Commun. 2008 Sep 5;373(4):648-52
All:	1 reference(s)