Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Padi6tm1.1Jgo
Name:	peptidyl arginine deiminase, type VI; targeted mutation 1.1, Jan A Gossen
MGI ID:	MGI:3806009
Gene:	Padi6  Location: Chr4:140454666-140469954 bp, - strand  Genetic Position: Chr4, 72.26 cM, cytoband E1
Alliance:	Padi6tm1.1Jgo page

Germline Transmission:	Earliest citation of germline transmission: J:138684
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Germ line, cre-mediated recombination was used to remove exons 2 and 3. The absence of protein expression was confirmed by immunohistochemistry on ovaries. (J:138684)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	8 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Padi6 Mutation:	31 strains or lines available

Original:	J:138684 Esposito G, et al., Peptidylarginine deiminase (PAD) 6 is essential for oocyte cytoskeletal sheet formation and female fertility. Mol Cell Endocrinol. 2007 Jul 15;273(1-2):25-31
All:	4 reference(s)