Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Fmn1tm1Made
Name:	formin 1; targeted mutation 1, Markus Dettenhofer
MGI ID:	MGI:3799352
Synonyms:	EGFP-Fmn1-IV
Gene:	Fmn1  Location: Chr2:113158081-113547112 bp, + strand  Genetic Position: Chr2, 57.3 cM, cytoband C1-qter
Alliance:	Fmn1tm1Made page

Germline Transmission:	Earliest citation of germline transmission: J:137209
Parent Cell Line:	TC1/TC-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: An EGFP gene was inserted inframe directly upstream of exon 6 to create a fusion product. A floxed neo cassette was also inserted upstream of exon 6 but was removed by germ line, cre-mediated recombination. (J:137209)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fmn1 Mutation:	75 strains or lines available

Original:	J:137209 Dettenhofer M, et al., Formin 1-isoform IV deficient cells exhibit defects in cell spreading and focal adhesion formation. PLoS One. 2008;3(6):e2497
All:	1 reference(s)