Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Canxtm1.1Osb
Name:	calnexin; targeted mutation 1.1, Research Institute for Microbial Diseases, Osaka University
MGI ID:	MGI:3798916
Synonyms:	Canxtm1.1Maik, tm1c
Gene:	Canx  Location: Chr11:50184788-50216500 bp, - strand  Genetic Position: Chr11, 30.46 cM
Alliance:	Canxtm1.1Osb page

Germline Transmission:	Earliest citation of germline transmission: J:136971
Parent Cell Line:	D3 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion     Exons 3 and 4 were flanked by loxP sites and subsequently deleted by cre-mediated recombination. (J:250114)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Canx Mutation:	54 strains or lines available

Original:	J:136971 Okiyoneda T, et al., Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and DeltaF508 CFTR. Biochim Biophys Acta. 2008 Sep;1783(9):1585-94
All:	2 reference(s)