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Ssh3tm1Taue
Targeted Allele Detail
Summary
Symbol: Ssh3tm1Taue
Name: slingshot protein phosphatase 3; targeted mutation 1, Tadashi Uemura
MGI ID: MGI:3796064
Gene: Ssh3  Location: Chr19:4311696-4319208 bp, - strand  Genetic Position: Chr19, 3.96 cM
Alliance: Ssh3tm1Taue page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:136245
Parent Cell Line:  TT2 (ES Cell)
Strain of Origin:  (C57BL/6NCrlj x CBA/JNCrlj)F1
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsPart of exon 1 downstream of the initiation codon and exon 2 were replaced with a lacZ and neo cassette. The absence of protein product was confirmed by western blot analysis on kidney extracts. This is a null allele and a reporter allele. (J:136245)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ssh3 Mutation:  25 strains or lines available
References
Original:  J:136245 Kousaka K, et al., Slingshot-3 dephosphorylates ADF/cofilin but is dispensable for mouse development. Genesis. 2008 May;46(5):246-55
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory