Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dpysl4tm1Ttq
Name:	dihydropyrimidinase-like 4; targeted mutation 1, Tam T Quach
MGI ID:	MGI:3790672
Synonyms:	CRMP3-
Gene:	Dpysl4  Location: Chr7:138665917-138681711 bp, + strand  Genetic Position: Chr7, 83.92 cM
Alliance:	Dpysl4tm1Ttq page

Germline Transmission:	Earliest citation of germline transmission: J:134800
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 3 was replaced with an IRES-lacZ-neo cassette. The absence of protein product was confirmed by western blot analysis on hippocampus extracts. This is a null allele and a reporter allele. (J:134800)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Dpysl4 Mutation:	35 strains or lines available

Original:	J:134800 Quach TT, et al., CRMP3 is required for hippocampal CA1 dendritic organization and plasticity. FASEB J. 2008 Feb;22(2):401-9
All:	3 reference(s)