Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Glis2tm1Amj
Name:	GLIS family zinc finger 2; targeted mutation 1, Anton M Jetten
MGI ID:	MGI:3785519
Synonyms:	Glis2mut
Gene:	Glis2  Location: Chr16:4412577-4442788 bp, + strand  Genetic Position: Chr16, 2.45 cM, cytoband A1-B1
Alliance:	Glis2tm1Amj page

Germline Transmission:	Earliest citation of germline transmission: J:134208
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exon 6 was replaced with a neo cassette resulting in a truncation of the protein product such that the fourth and fifth zinc finger motifs are absent. (J:134208)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Glis2 Mutation:	102 strains or lines available

Original:	J:134208 Kim YS, et al., Kruppel-like zinc finger protein Glis2 is essential for the maintenance of normal renal functions. Mol Cell Biol. 2008 Apr;28(7):2358-67
All:	4 reference(s)