Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Card6tm1.1Aldu
Name:	caspase recruitment domain family, member 6; targeted mutation 1.1, Almut Dufner
MGI ID:	MGI:3776908
Gene:	Card6  Location: Chr15:5125463-5138021 bp, - strand  Genetic Position: Chr15, 1.99 cM
Alliance:	Card6tm1.1Aldu page

Germline Transmission:	Earliest citation of germline transmission: J:132634
Parent Cell Line:	E14K (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: The last coding exon was removed by germ-line, cre-mediated recombination. The absence of protein product was confirmed by western blot analysis on thymus and bone marrow extracts. (J:132634)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Card6 Mutation:	54 strains or lines available

Original:	J:132634 Dufner A, et al., CARD6 is interferon inducible but not involved in nucleotide-binding oligomerization domain protein signaling leading to NF-kappaB activation. Mol Cell Biol. 2008 Mar;28(5):1541-52
All:	1 reference(s)