Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lsamptm1Afpi
Name:	limbic system-associated membrane protein; targeted mutation 1, Aurea Fugazzola Pimenta
MGI ID:	MGI:3773703
Gene:	Lsamp  Location: Chr16:39804723-42002042 bp, + strand  Genetic Position: Chr16, 28.26 cM, cytoband B5
Alliance:	Lsamptm1Afpi page

Germline Transmission:	Earliest citation of germline transmission: J:131383
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Part of exon 2 and intron 2 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on cerebellum extracts. (J:131383)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lsamp Mutation:	25 strains or lines available

Original:	J:131383 Catania EH, et al., Genetic deletion of Lsamp causes exaggerated behavioral activation in novel environments. Behav Brain Res. 2008 Apr 9;188(2):380-90
All:	1 reference(s)