Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(tetO-Clock)1Jt
Name:	transgene insertion 1, Joseph S Takahashi
MGI ID:	MGI:3772938
Synonyms:	tetO::Clockwt, Tg(tetO-Clock)isoJt
Transgene:	Tg(tetO-Clock)1Jt  Location: unknown
Alliance:	Tg(tetO-Clock)1Jt page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Inducible, Inserted expressed sequence) Inducer:    doxycycline/tetracycline Mutation:    Insertion   Tg(tetO-Clock)1Jt expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Clock (MGI:99698)   Mutation details: A transgenic vector was designed to carry the full-length wildtype mouse Clock gene downstream of a tetracycline-responsive promoter (TRE; tetO). Crossing these mice with mice expressing the tTA or reverse tetracycline-controlled transactivator protein under control of tissue-specific promoters, transgene expression can be regulated in appropriate tissues in the offspring with administration of the tet analog doxycycline. (J:120326)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:120326 Hong HK, et al., Inducible and reversible Clock gene expression in brain using the tTA system for the study of circadian behavior. PLoS Genet. 2007 Feb 23;3(2):e33
All:	2 reference(s)