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n-TUtca2tm2.1Mym
Targeted Allele Detail
Summary
Symbol: n-TUtca2tm2.1Mym
Name: nuclear encoded tRNA selenocysteine 2 (anticodon TCA); targeted mutation 2.1, Masayuki Yamamoto
MGI ID: MGI:3772693
Synonyms: Trspdel
Gene: n-TUtca2  Location: Chr7:19035169-19035255 bp, + strand  Genetic Position: Chr7, 9.56 cM
Alliance: n-TUtca2tm2.1Mym page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130723
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
    The transcriptional unit was removed by germ-line, cre-mediated recombination. (J:130723)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any n-TUtca2 Mutation:  2 strains or lines available
References
Original:  J:130723 Suzuki T, et al., Deletion of the selenocysteine tRNA gene in macrophages and liver results in compensatory gene induction of cytoprotective enzymes by Nrf2. J Biol Chem. 2008 Jan 25;283(4):2021-30
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory