Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ahrrtm1Yfk
Name:	aryl-hydrocarbon receptor repressor; targeted mutation 1, Yoshiaki Fujii-Kuriyama
MGI ID:	MGI:3772082
Synonyms:	AhRR-
Gene:	Ahrr  Location: Chr13:74359237-74440450 bp, - strand  Genetic Position: Chr13, 40.15 cM, cytoband C2
Alliance:	Ahrrtm1Yfk page

Germline Transmission:	Earliest citation of germline transmission: J:130214
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Part of exon 2 and intron 2 were replaced with a lacZ cassette with a nuclear localization signal and a neo cassette. The absence of transcript upon induction with 3-methylcholanthrene was confirmed by RT-PCR analysis of spleen extracts. (J:130214)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ahrr Mutation:	33 strains or lines available

Original:	J:130214 Hosoya T, et al., Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice. Biochem Biophys Res Commun. 2008 Jan 18;365(3):562-7
All:	2 reference(s)