Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Ube3atm2Alb
Name:	ubiquitin protein ligase E3A; targeted mutation 2, Arthur L Beaudet
MGI ID:	MGI:3771814
Synonyms:	Ube3aYFP
Gene:	Ube3a  Location: Chr7:58878498-58961284 bp, + strand  Genetic Position: Chr7, 33.95 cM
Alliance:	Ube3atm2Alb page

Germline Transmission:	Earliest citation of germline transmission: J:130068
Parent Cell Line:	AB2.2 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Reporter) Mutation:    Insertion   Mutation details: Exon 10 was fused to YFP and a floxed neo cassette was inserted downstream of it to produce expression of YFP that recapitulates endogenous expression. (J:130068)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ube3a Mutation:	68 strains or lines available

Original:	J:130068 Dindot SV, et al., The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology. Hum Mol Genet. 2008 Jan 1;17(1):111-8
All:	6 reference(s)