Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bnc1tm1.1Tsen
Name:	basonuclin zinc finger protein 1; targeted mutation 1.1, Hung Tseng
MGI ID:	MGI:3771811
Synonyms:	Bnc1-
Gene:	Bnc1  Location: Chr7:81616401-81642047 bp, - strand  Genetic Position: Chr7, 45.71 cM
Alliance:	Bnc1tm1.1Tsen page

Germline Transmission:	Earliest citation of germline transmission: J:130266
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exon 4 was removed by germ-line, cre-mediated recombination resulting a premature stop codon and a frame shift. The absence of transcript was confirmed by RT-PCR and the absence of protein product was confirmed by immunohistochemistry. (J:130266)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bnc1 Mutation:	27 strains or lines available

Original:	J:130266 Zhang X, et al., Basonuclin-null mutation impairs homeostasis and wound repair in mouse corneal epithelium. PLoS One. 2007;2(10):e1087
All:	2 reference(s)