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Slc17a6tm1Lowl
Targeted Allele Detail
Summary
Symbol: Slc17a6tm1Lowl
Name: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6; targeted mutation 1, Bradford B Lowell
MGI ID: MGI:3771177
Synonyms: Vglut2flox
Gene: Slc17a6  Location: Chr7:51271754-51320867 bp, + strand  Genetic Position: Chr7, 32.78 cM, cytoband B4
Alliance: Slc17a6tm1Lowl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:129860
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsLox P sites were inserted upstream and downstream of exon 2. A neo cassette used for selection purposes was removed by flp-mediated recombination. (J:129860)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Slc17a6 Mutation:  59 strains or lines available
References
Original:  J:129860 Tong Q, et al., Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia. Cell Metab. 2007 May;5(5):383-93
All:  39 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory