Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cst7tm1Ayr
Name:	cystatin F (leukocystatin); targeted mutation 1, Alexander Y Rudensky
MGI ID:	MGI:3770401
Synonyms:	cystatin F-
Gene:	Cst7  Location: Chr2:150412335-150420864 bp, + strand  Genetic Position: Chr2, 74.67 cM, cytoband G1-G3
Alliance:	Cst7tm1Ayr page

Germline Transmission:	Earliest citation of germline transmission: J:129915
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A targeting vector was designed to replace exons 2, 3 and 4 with a PGK-neomycin resistance cassette in reverse orientation. No expression is detected in dendritic cells, macrophages, or B cells. (J:129915)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cst7 Mutation:	18 strains or lines available

Original:	J:129915 Rudensky AY, Generation of a Cst7 null allele. MGI Direct Data Submission. 2008;
All:	2 reference(s)