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Actbtm2.1Npa
Targeted Allele Detail
Summary
Symbol: Actbtm2.1Npa
Name: actin, beta; targeted mutation 2.1, Novartis Pharma AG
MGI ID: MGI:3769439
Synonyms: FRT/Credel
Gene: Actb  Location: Chr5:142888870-142892509 bp, - strand  Genetic Position: Chr5, 81.8 cM
Alliance: Actbtm2.1Npa page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:129105
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  BALB/c
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Intragenic deletion
 
Mutation detailsActbtm2Npa mice were crossed with a cre-deleter strain to remove the floxed stop codon upstream of the EGFP reporter gene. Strong EGFP expression was observed in numerous tissues including brain, heart and kidney. (J:129105)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Actb Mutation:  51 strains or lines available
References
Original:  J:129105 Jagle U, et al., Conditional transgene expression mediated by the mouse beta-actin locus. Genesis. 2007 Nov;45(11):659-66
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory