Analysis Tools
endocrine/exocrine glands
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• 60% of females exhibit a relatively normal ovarian morphology with developing and antral-stage follicles, although with fewer follicles than in wild-type
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• 40% of females exhibit residual ovaries devoid of follicles
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reproductive system
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• spermatocytes exhibit either a zygotene-like or aberrant pachytene-like morphology, containing a mixture of synapsed, partially synapsed and asynapsed chromosomes
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• 60% of females exhibit a relatively normal ovarian morphology with developing and antral-stage follicles, although with fewer follicles than in wild-type
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• 40% of females exhibit residual ovaries devoid of follicles
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• testes undergo complete prophase I meiotic arrest, without signs of postmeiotic differentiation as is seen in heterozygous Dmc1Mei11 males
• defective chromosome synapsis and double strand break repair in spermatocytes; spermatocytes exhibit either a zygotene-like or aberrant pachytene-like morphology, containing a mixture of synapsed, partially synapsed and asynapsed chromosomes
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cellular
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• spermatocytes exhibit either a zygotene-like or aberrant pachytene-like morphology, containing a mixture of synapsed, partially synapsed and asynapsed chromosomes
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