Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Bcl11btm1Avram
Name:	B cell leukemia/lymphoma 11B; targeted mutation 1, Dorina Avram
MGI ID:	MGI:3767620
Synonyms:	BCL11BF
Gene:	Bcl11b  Location: Chr12:107876662-107969861 bp, - strand  Genetic Position: Chr12, 59.1 cM, cytoband F1
Alliance:	Bcl11btm1Avram page

Germline Transmission:	Earliest citation of germline transmission: J:128515
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     Exon 3, which includes most of the gene's coding sequence, was flanked by LoxP sites. (J:128515)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bcl11b Mutation:	45 strains or lines available

Original:	J:128515 Albu DI, et al., BCL11B is required for positive selection and survival of double-positive thymocytes. J Exp Med. 2007 Nov 26;204(12):3003-15
All:	10 reference(s)