Summary | Mutation origin | Mutation description | Find Mice (IMSR) | Notes | References

Symbol:	Ctnnb1tm1Knw
Name:	catenin beta 1; targeted mutation 1, Barbara B Knowles
MGI ID:	MGI:3767601
Synonyms:	betaCatCf
Gene:	Ctnnb1  Location: Chr9:120762466-120789573 bp, + strand  Genetic Position: Chr9, 72.19 cM
Alliance:	Ctnnb1tm1Knw page

Germline Transmission:	Earliest citation of germline transmission: J:232771
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	C57BL/6J

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A targeting construct was used to flank exons 8 to 13 with loxP sites and insert an FRT-flanked NEO cassette into intron 13. The loxP flanked region is designed to remove amino acids 361 to 692, which encompasses a part of armadillo repeat 6 to a part of the C terminus. (J:232771)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ctnnb1 Mutation:	49 strains or lines available

Original:	J:232771 Messerschmidt D, et al., beta-catenin-mediated adhesion is required for successful preimplantation mouse embryo development. Development. 2016 Jun 1;143(11):1993-9
All:	7 reference(s)